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Acute Asthma Exacerbation (Epidemiology (Race/Ethnicity (African-American…
Acute Asthma Exacerbation
Clinical Presentation
Hyperventilation
Decreased expiratory airflow
ABG
Decreased PaCO2
Increased pH
Chest tightness
Wheezing, dyspnea, cough
Epidemiology
Acute illness (rhinovirus, coronavirus, influenza, etc.)
Race/Ethnicity
African-American patients have a higher risk than Caucasians
Weather (humidity, winter months, increased heat index, etc.)
Obesity
GERD
Sleep-disordered breathing
Pathophysiology
Vasodilation
Mucosal Edema
Bronchospasms
Mucus Secretion
Increased capillary permeability
Narrow airway/airflow obstruction