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Female Genital Function and Hormone (Hypothalamus (GnRH (Pituitary…
Female Genital Function
and Hormone
Hypothalamus
GnRH
Pituitary
FSH：Stimulates ovarian follicle development;with luteinizing hormone,stimulates
secretion of estrogen and ovulation.
Ovary
Estrogen：Development of reproductive organs
during puberty.Development of secondary sex
characteristics,including breast
maturation,widening of pelvis,and
distribution of fat and muscle tissuesin a distinctively female pattern.
Cyclic preparation of endometriumfor implantation of an ovum.
Reduce cholesterol.
Too high
Proliferation of
the endometrium
Uterine
Leiomyomas
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Endometriosis
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Endometrial
Cancer
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Breast cell
hyperplasia
Breast
Cancer
Inhibition
GnRH
Amenorrhea
Progesterone：Cyclic preparation and maintenance
of endometrium for implantation of an ovum. Stimulation of development of breast lobes and
alveoli.
Too high
Breast cell
hyperplasia
Breast
cancer
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Block
Insulin
DM
Gestational
diabetes(+HPL)
Too low
Abortion
Vaginal Bleeding and abdominal cramps
LH：Stimulates final development of ovarian
follicle,process of ovulation, and
development of corpus luteum.
GnRH
Pituitary
FSH ↑
Ovary Follicle
Estrogen ↑
Uterus
Proliferative
LH ↑
Ovary Luteum
Progesterone ↑
Uterus
Secretory phase
Pituitary
FSH ↓ , LH ↓
Ovary
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Stress and Hormone
Hypothalamus
Stress in ：CRH ↑、GnRH ↓
Pituitary
Stress in ：ACTH ↑
Adrenal cortex
cortisol