6.Monitor closely for 15–30 minutes to detect signs of reaction. Monitor vital signs at regular intervals per institution or agency policy; compare results with baseline measurements. Increase frequency of measurements based on patient’s condition. Observe patient frequently throughout the transfusion for any signs of adverse reaction, including restlessness, hives, nausea, vomiting, torso or back pain, shortness of breath, flushing, hematuria, fever, or chills. Should any adverse reaction occur, stop infusion immediately, notify primary provider, and follow the agency’s transfusion reaction standard.