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Infant with Sickle Cell Disease (downstream effects (skeletal system…
Infant with Sickle Cell Disease
Background info
psychology
cell structure
nucleolus
ribosome assemble
nucleus
DNA
nuclear envelope
separate DNA from Cytoplasm
plasma membrane
separate inside & outside of cell
mitochondria
make ATP
ribosomes
makes proteins
golgi apparatus
package proteins/forms lysosomes
rough endoplasmic reticulum
make proteins/ send to golgi apparatus
centrioles
Cell division
smooth endoplasmic reticulum
lipid/steroid synthesis & lipid metabolism
organelles
endoplasmic reticulum
manufacturing package system
golgi apparatus
package proteins/forms lysosomes
lysosomes
waste/break down/recycle
mitochondria
make ATP
peroxisomes
lipid metabolism/chemical detoxification
cytoskeleton
cell support structure
macromolecules
lipids
fatty acid monomers
store energy
EX fats/oil
protein
amino acid monomers
transport molecules muscle movement
EX hemoglobin/antibodies
carbohydrate
sugar monomers
energy storage
EX sugar
nucleic acids
nucleotide monomers
instruction for protein synthesis
EX DNA/RNA
DNA
Nucleotides
adenine
guanine
thymine
cytosine
protein structure
secondary
amine group/carboxylic acid groups attract
alpha helices/beta sheets
tertiary
3d shape
primary
sequence of amino acids in protein
quaternary
amino acid chain interact with each other
chemical bonds
ionic bonds
cations/anions
steal electron from another
hydrogen bonds
opposite attract
dipoles form
covalent bonds
polar
not equal
hydrophibic
nonpolar
equally
hydrophobic
mitosis
metaphase
chromosomes lined up, center of cell
anaphase
chromosomes split in half, opposite ends
dividing cell
prophase
DNA condenses into chromosomes
telophase
new nuclei around DNA
two new cells
Anatomy
cell structure
nucleolus
nucleus
nuclear envelope
plasma membrane
mitochondria
ribosomes
golgi apparatus
rough endoplasmic reticulum
centrioles
smooth endoplasmic reticulum
organelles
endoplasmic reticulum
golgi apparatus
lysosomes
mitochondria
peroxisomes
cytoskeleton
cell macromolecules
proteins
nucleic acids
lipids
carbohydrates
DNA forms
guanine
thymine
adenine
cytosine
Amino acids
polar
polar basic (positive charge)
Nonpolar
polar acidic (negative charge)
protein structure
tertiary
Quaternary
secondary
primary
chemical bonds
covalent bonds
hydrogen bonds
ionic bonds
downstream effects
cardiovascular system
heart
possible failure
heart attacks
ocular system
eyes
damage
skeletal system
bones
damage
joints
pain
digestive system
gallbladder
gallstones
liver
sickle cell crisis
renal system
kidneys
damage
loss body water in urine
immune system
chronic anemia
infection
respiratory system
lungs
infections
asthma
pneumonia
acute chest syndrome
lymphatic system
spleen
splenic crisis
splenic sequestration (pooling)
nervous system
stroke
upstream effects
specific cause
inherited gene by parent
indirect cause
DNA sequence mutation
direct cause
banana shape red blood cells
if get through
not enough oxygen
can't get to blood vessels