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GLOMERULONEPHRITIS (Nephrotic Sd (Presentation (Heavy prot >3.5g/day,…
GLOMERULONEPHRITIS
Nephrotic Sd
Presentation
Heavy prot >3.5g/day
Hypoalbuminemia
Generalized edema
Hyperlipidemia and fatty casts (urine)
Hypertension
↑ risk of thromboembolisms and infxn
Causes
Minimal Change disease
Focal Segmental glomerulosclerosis
Membranous nephrotpathy
Membranoproliferative glomerulonephritis
Diabetic nephropathy
Lupus nephritis
Nephritic Sd
Presentation
Prot <3.5g/day
Hematuria w/ acathocytes
RCB casts on urine
Mild/moderate edema
Hypertension
Oliguria
Causes
PSGN
IgA Nephropathy
Granulomatosis w/ poliangiitis (Wegener)
Microscopic polyangiitis
Churg-Strauss Sd
Goodpasture Sd
Alport Sd
Thin basement membrane
RPGN
Lupus Nephritis
Definition
Damage to the glomeruli that disrupts the filtration process
appearance of blood components (proteins and red blood cells) in the urine