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Patient with uncontrolled diabetes (A wound is formed (Hemostasis…
Patient with uncontrolled diabetes
A wound is formed
Hemostasis
Inflammatory Response
Proliferation
1.) Granulation tissue develops
Angiogenesis
2.) Epithelium develops
3.) Collagen formation
Extracellular matrix is synthesized
Maturation
Inflammation is decreased
Long JE forms
Newly formed scar tissue has less strength than original tissue
PMN cells respond
PMN cells "wall-off" bacteria
PMN function is reduced due to uncontrolled diabetes
Epinephrine is released by platelets
Cytokines released to assist with healing
Cytokine function is reduced due to uncontrolled diabetes