Please enable JavaScript.

Coggle requires JavaScript to display documents.

Healing Time Lines (Uncontrolled Diabetes (Delayed healing due to systemic…

- - - - Decreased Inflammation due to impaired PMN and chemotaxis
        
        Decreased Proliferation due to lack of chemotaxis less granulation tissue. Will take longer and require more collagen to fill in the matrix.
        
        Maturation will take longer due to previous steps
- - - - Activation is from damaged vessel wall, platelets, blood proteins
      - Prothrombin activator is formed via external pathway (vessels and surrounding tissue) or intrinsic pathway (blood itself)
      - Need calcium in adequate quantities to convert prothrombin to thrombin
      - Thrombin then causes polymerization of fibrinogen in fibrin fibers
      - These fibers create mesh for clot
      - Neutrophils
        
        PMN’s destroy bacteria in the beginning
        
        Macrophages then take over and attack after about 4 days
        
        These cells uses chemokines to call for help from other cells
        
        Proliferation
        
        Angiogenesis (Building BV)and Granulation tissue formation
        
        Epithelium attachment remains at original height
        
        This produces a long junctional epithelium
        
        Granulation tissue penetrates thin clot, permitting fibers extending from cementum to unite with the new collagen formed by gingival fibroblasts
        
        Fibroblasts stimulate collagen to get tensile strength
        The wound fills with granulation tissue contracting the wound
        
        Maturation
        
        Need nutrition from blood to form epithelial
        
        Scar tissue forms
        
        Less strong than original
        
        Due to poor homecare maturation will be compromised bacteria will be able to break through scar tissue easily putting patient at higher risk for attachment loss periodontist.