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skeletal muscle (structure (neuromuscular junction (formed with myelinated…
skeletal muscle
structure
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thick and thin filaments
myosin
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two globular heads extend out, forming cross-bridges
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tropomyosin
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overlaps binding sites on actin for myosin and inhibits interaction when in relaxed state, won't allow contraction to occur
troponin
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binds Ca2+ reversibly and once bound changes conformation to pull tropomyosin away from myosin interaction sites
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motor units
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one motor neuron innervates many muscle fibers, but one muscle fiber is innervated by only one motor neuron
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Transverse tubule
Na+ charge enters here, where it can be introduced to sarcoplasmic reticulum
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contraction
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muscles prevented from contracting whenever they want by troponin complex blocking cross bridge from actin
when Ca2+ binds to troponin, pulls tropomyosin away from myosin interaction sites
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