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NEPHROTIC SYNDROME (Management (Immunosupprsessive agents maybe prescribed…
NEPHROTIC SYNDROME
Management
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Give diuretics to manage oedema and a srict intake and output should be measured and reported to avoid too much fluid loss.
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Symptoms
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On children ; fatigue and malaise, decreased appetite, facial swelling , abdominal swelling and pain and foamy urine .
Causes
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Infections like herpes zoster, chronic diseases like diabetes mellitus and cancers
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Pathophysiology
When glomerular basement membrane is damaged there is an increase in permeability that initially allows proteins of small molecular weight to leak out through the bowmans caspsule and proximal tubule.
As the condition worsens ,larger proteins like albumin also leak out and are excreted in urine.
As the body continues to lose proteins , serum albumin is decresed resulting in a decrease in osmotic pressure.
Definition
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Nephrotic syndrome is not a disease in itself ,but it describes the clinical manifestations that result from other renal diseases that are present simultaneously .