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NEUROLOGICAL DISEASES (ALS (limb onset (selectively affects the motor…

- - - - motor neurons destroyed; astrocytes & motor neurons; astrocytes = release growth factors & remove glutamate; disrupted glutamin- glutamate cycling in astrocytes
  - - - spasticity = different than rigidity in that one direction increased tone and the other not; spasticity is damage to corticoreticalspinal (pyramidal) tracts
- - - - rigid = rigidity is different than spasticity in that increased tone remains constant throughout range of movement