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How "roids" could cause testicular shrinkage and if there are…
How "roids" could cause testicular shrinkage and if there are other side effects he could experience (note T is Testosterone and this coggle is applicable male patients only)
occurs as T release acts on testes via a negative feedback mechansim to inhibit the release of further T
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by supplementing exogenous T, the user triggers the negative feedback loop inhibiting the release of further T. The abundance of T present leads to down regulation of T receptors effectively causing desensitization, otherwise known as tolerance in this case.
Continuing to abuse steroids will at minimum keep the T-producing cell population and T-receptor population in the testes to a minimum and ceasing consumption of T will to some extent reverse this process.
endocrine system - interacts with nervous system to coordinate and integrate the activity of body cells
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