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SUBSTANCE ABUSE / TOXINS - alcohol (*Alcoholism and Quitting 1st line =…
SUBSTANCE ABUSE / TOXINS - alcohol
*Metabolism of Alcohol
Fomepizole and Disulfiram
*Disulfiram
what gives the hang over effect after alcohol
disulfiram blocks acetaldehyde DH
causes accumulation of acetaldehyde
*Disulfiram like reaction
what gives the hang over effect after alcohol
causes accumulation of acetaldehyde
can be caused by antibuotics and especially if they are taken with alcohol
*Alcoholism and Quitting
1st line =
naltrexone
--> oppioid antagonist
--> blocks cravings and reward from alcoholism
alcoholics use Naloxone TRIX to stop
nalaxone TRIX = naltrexone
2nd line =
acamprosate
--> NMDA modulator
--> A camp PRO ain't no alcoholic
--> A camp PRO ain't = acamprosate
3rd line =
disulfiram
--> aldehyde DHD antagonist
-->
DIE and SUFFER with disufiram
*Alcoholism Withdrawals
Life-threatening, counterintuitive but need to stop Alcohol withdrawal seizures first, then DeTOX delerium tremins
--> use Benzos that act at GABA same as alcohol
--> counterintuitive that you have to give them their fix
"2-4 day NO Bender DeTox for alcoholics"
1st line =
Benzos
-->
LORAZ
and
DIAZ
--> lorazapam, diazapam, chlordiazapoxide
"2-4 day NO Bender DeTox for alcoholics"
2-4 day DeTox
= DT = delerium tremens happens 2-4 days after last drink
after 12 hours seizures can set in before the DT
No Bender
= treat alcohol withdrawal with Benzos
Alcohol HITS you hard
H = halucinations
I = Insomnia and increase in Vital sins
T = tremens delerium
S = Seizures, shakes, sweats
*DT = Delerium Tremens
acoholic withdrawal symptrom that is LIFE-threatening
"2-4 day NO Bender DeTox for alcoholics"
2-4 day DeTox
= DT = delerium tremens happens 2-4 days after last drink
No Bender
= treat alcohol withdrawal with Benzos
*Alcoholism and Quitting
1st line =
naltrexone
--> oppioid antagonist
--> blocks cravings and reward from alcoholism
alcoholics use Naloxone TRIX to stop
nalaxone TRIX = naltrexone
2nd line =
acamprosate
--> NMDA modulator
--> A camp PRO ain't no alcoholic
--> A camp PRO ain't = acamprosate
3rd line =
disulfiram
--> aldehyde DHD antagonist
-->
DIE and SUFFER with disufiram
*Alcoholism Withdrawals
Life-threatening, counterintuitive but need to stop Alcohol withdrawal seizures first, then DeTOX delerium tremins
--> use Benzos that act at GABA same as alcohol
--> counterintuitive that you have to give them their fix
"2-4 day NO Bender DeTox for alcoholics"
1st line =
Benzos
-->
LORAZ
and
DIAZ
--> lorazapam, diazapam, chlordiazapoxide
DT = Delerium Tremens
acoholic withdrawal symptrom that is LIFE-threatening
"2-4 day NO Bender DeTox for alcoholics"
2-4 day DeTox
= DT = delerium tremens happens 2-4 days after last drink
No Bender
= treat alcohol withdrawal with Benzos
"2-4 day NO Bender DeTox for alcoholics"
2-4 day DeTox
= DT = delerium tremens happens 2-4 days after last drink
after 12 hours seizures can set in before the DT
No Bender
= treat alcohol withdrawal with Benzos
