Please enable JavaScript.
Coggle requires JavaScript to display documents.
BCHM OF RBC (BASIC MORPHOLOGY (Membrane structure: lipid bilayer for…
BCHM OF RBC
BASIC MORPHOLOGY
-
Transports O2 from lungs to tissues, disposes of CO2 and H+ via exhalation (Cl-/HCO3- antiporter to transport CO2 from periphery to lungs)
-
-
-
Membrane structure: lipid bilayer for fluidity and flexibility, 50% protein, 40% fat, 10% carb
- Glycophorins A-C: transmembrane glycoproteins
- a and b spectrin aligned anti-//
- Actin binds to tail of spectrin and Protein 4.1
- Ankyrin binds Spectrin and to Band 3 (Cl-/HCO3- exchanger)
- Protein 4.1
-
[K+, Mg2+, Zn2+] higher in RBC than plasma
FATE OF THE RBC
-
Tetrapyrole component of heme converted to bilirubin, excreted in bile
-
METABOLISM
-
GLUCOSE TRANSPORT
Facilitated diffusion through GLUT-1 (insulin INdependent), generates a pore in membrane for glucose to enter
-