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Cannabinoid (Treatment (Immunomodulator (Inhibit TLR-induced inflammatory…
Cannabinoid
Treatment
Analgesics
Antioxidant
Prevention neurodegenerative disorder :star:
Alzheimer's disease
Parkinson's disease
Mutiple sclerosis :star:
Prevention cardiovascular disease
Increase apoptosis and inhibit cell proliferation
Autoimmune disease
Mutiple sclerosis
Anti-microbial
Anti-cancer
tumor microenvironment
Pro-inflammatory cytokine
stimulate EGFR
Cell growth
Invasion
Cell migration
Immunomodulator
Inhibit TLR-induced inflammatory response
Pro-inflammatory cytokine
Inhibit adenylate cyclase activity
Anti-inflammation
Inflammatory bowel disease
Clostridium difficile
associated colitis
Species
C.sativa
:star:
Chemical structure
C.indica
C.ruderalis
Project
Experimental system
Pre-cinical study
Lung carcinoma
Gilioma
Thyroid epithelioma
Lymphoma/Leukemia
Skin carcinoma
Uterus carcinoma
Breast cancer
Prostate carcinoma
Neuroblastoma
Hallmark of cancer
Substaing proliferative signaling
Evading growth suppressor
Avoid immune desrtuction
Enabling replicative immortally
Tumor promoting inflammation
Active invasion & metastasis
Inducing angiogenesis
Genome instability & mutation
Resistance cell death
Deregulatiing cellular energetics
Marker
Angiogenesis: VEGF
Differentiation: EGFR
Cell cycle: CDK1
Invasion: MMP-2
Endogenous ligand
Endocannabinoid system (ECS): ร่างกายสร้างเอง
Cannabinoid receptor
CB1: CNS
CB2: immune system
Immunomodulatory properties
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