Ulcerative Colitis
Definition
Condition in which interminent inflammation and
Ulceration of the mucosa of the colon occurs
Causes
Infectious agents
Food additives
Pesticides
Radiation
Tobacco
Heredity, genetic disorders
Pathophysiology
Inflammantory process is often continues
It is superficial but may extend over a large area
And necrosis
Characteristics lesions form in the crypts of lieberkuhn
With oedema and multiple areas of desquarnation
Found in the base of mucosal layer
Often presents as diffuse inflammation of colonic mucosa
And eventually form crypt abscess
Clinical manifestations
Diarrhoea
Noctural diarrhoea
Dehydration and weight loss
Amount of blood in stool is present
Anorexia and vomiting
Tachycardia, hypotensive and tachypnoea
Diagnostic tests
Sigmoidoscopy
X-ray
Heamatological studies
Pharmacological treatment
Cyclosporine
Corticosteroids
ANti-inflammantory
Infliximab
Antibiotics
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Nursing intervetion
relief pain with analgesics as prescribed
Control diarrhoea
Improve nutrition
Relieving anxiety
Enhance coping mechanisms
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Avoid lactose in milk
Avoid caffeine
Avoid highly spiced food
Eat fibre supplements to control diarrhoea