Please enable JavaScript.
Coggle requires JavaScript to display documents.
Fructose Metabolism (Steps (Fructose Phosphorylation (is catalyzed by…
Fructose Metabolism
Steps
Fructose Phosphorylation
is catalyzed by
hexokinase
Fructokinase
produces
Fructose 1-P
Fructose 1-Phosphate Clevage
is catalyzed by
Aldolase A
is found in
most tissues
Aldolase B
is found in
liver
kidney
small intestines
Aldolase C
is found in
brain
produces
Glyceraldehyde 3-Phosphate
DHAP
Disorders
Essential fructosuria
Sxs
polyruia
polyphagia
dehydration
is caused by
deficiency of fructokinase
causes
increased levels of fructose in blood
HFI (Hereditary Fructose Intolerance)
Sxs
Increased AMP/ATP ratio
hyperuricemia
lactic acidemia
decreased gluconeogenesis
hypoglycemia
vomiting
causes
accumulation of Fructose 1-Phosphate in tissues
is caused by
deficiency of Aldolase A/B/C