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Glycolysis (Pathway (1) Glucose Phosphorylation (is catalyzed by…

- - - - Hexokinase I-IV
    - - Glucose into Glucose 6 P
    - - [] Fructose 6P
  - - - Glucose 6 P into Fructose 6 P
    - - Phosphoglucose isomerase
    - - N/A
  - - - PFK-1/PFK-2
    - - Fructose 6-P into Fructose 1,6 P
    - - Insulin
        
        which causes
        
        increased PFK2 activity
      - Glucagon
        
        which causes
        
        decreased PFK2 activity
  - - - Fructose 1,6 P into DHAP and Glyceraldehyde 3P
    - - Aldolase
    - - N/A
  - - - Triose phosphate isomerase
    - - freely reversible
    - - DHAP into Glyceraldehyde 3 P
  - - - Glyceraldehyde 3-phosphate dehydrogenase
    - - Glyceraldehyde 3-P into 1,3 Bisphosphoglycerate with production of NADH
    - - levels of NAD+
  - - - N/A
    - - phosphoglycerate kinase
    - - 1,3 Bisphosphoglycerate into 3-phosphoglycerate with the generation of ATP
  - - - Phosphoglycerate mutase
    - - 3-phosphoglycerate into 2-phosphoglycerate
    - - N/A
  - - - Enolase
    - - 2-phosphoglycerate into PEP
    - - N/A
  - - - Pyruvate Kinase
    - - PEP into Pyruvate with generation of ATP
    - - Fructose 1,6 P
        
        which causes
        
        increased PK activity
      - glucagon
        
        which causes
        
        decreased PK activity