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vitiligo (pathophysiology (Generally agreed upon principles are an absence…
vitiligo
pathophysiology
Generally agreed upon principles are an absence of functional melanocytes in vitiligo skin and a loss of histochemically recognized melanocytes, owing to their destruction.
Although several theories have been proposed about the pathogenesis of vitiligo, the precise cause remains unknown.
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symptoms
Premature whitening or graying of the hair, light hair colour
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White, well demarcated, oval macules and patches
causes
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It might show up due to stress, over exposure to sun or chemicals
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surgical management
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Skin grafting: A small part of the normal pigmented skin is removed and grafted in the discoloured areas.
Blister grafting: Small blisters are created in the normal pigmented area and these are placed on the affected area.
medical management
Corticosteroid: Help restore colour or aid repigmentation.
Betamethasone valerate . Clobetasol Propionate
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defination
A condition in which the melanocytes, the pigment cells of the skin, are destroyed causing affected areas to turn pale. Often seen as patches of white skin.