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LIVER FAILURE (ASSESSMENT FINDINGS AND SYMPTOMS (• SLEEPINESS, • …
LIVER FAILURE
DEFINITION
LIVER FAILURE IS THE INABILITY OF THE LIVER TO PERFORM IT NORMAL SYNTHESIS ND METABOLIC FUNCTION AS PART OF NORMAL PHYSIOLOGY
PATHOPHYSIOLOGY
IN THE MAJORITY OF THE ACUTE LIVER FAILURE THERE IS WIDESPREAD HEPATOCELLULAR NECROSIS BEGINNING IN THE CENTRIZONAL DISTRIBUTION AND PROGRESSING TOWARDS PORTAL TRACKS. THE DEGREE OF PARECHYMAL INFLAMMATION IS VAIRIABLE AND PROPORTIONAL TO THE DURATION OF THE DISEASE
RISK FACTORS
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• OBESITY, DIABETES OR HIGH CHOLE
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