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Protein Misfolding Diseases (Amyloid Diseases (Caused by (Amyloid B (AB)…
Protein Misfolding Diseases
Amyloid Diseases
Caused by
Amyloid B (AB)
which is
Extracellular component of Amyloid precursor protein
Neurofibrillary tangles and neurotoxicity
Tau protein
which is
involved in microtubule construction
Neurofibrillary tangles and neurotoxicity
Prion Diseases
Caused by
PrP protein
which is
expressed on surface of neurons and glial cells
Composed of Alpha Helixes
which become
Beta Sheets
Neurofibrillary tangles and neurotoxicity