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NEPHROTIC (Filtration barrier is lost (Loss of negative charge (Podocyte…
NEPHROTIC
Filtration barrier is lost
Loss of negative charge
Podocyte effacement
Intact RBC filtration layer
Cytokine damage
Fats lost: maltese cross (fatty casts), increased lipoprotein synthesis
Proteins loss: loss of AT3, hypercoagulability, renal vein thrombosis
@ podocytes: effacement and fusion
Minimal
Selective proteinuria
Minimal part of body: foot
FSGN
sclerotic, hyaline deposits
obliterated capillaries
Sickle cell
Heroin, Hepatitis, HIV
Deposition of IC
Membrano-proliferative
Proliferative: fast on the track
tram track
splitting
Type 1: Hep B and C: sub-endo
Type 2: intra-membranous: dense deposit disease
Membrano
Suck some dick to be a member of the club
Dome
IVDU
Hepatitis
Ab's against PLA-2 receptor
Systemic
DM
Mesangial expansion + GBM thickening
Hyaline: eosinophilic: KM Wilson nodes
Amyloidosis