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NEPHRITIC (Inflammation (Endothelial injury: glomerular bleed (Chemotactic…
NEPHRITIC
Inflammation
Immune complex
stuck @
Sub-endothelio: between capillary and BM
Sub-epithelia
PSG, MP
BM
Endothelial injury: glomerular bleed
Chemotactic: neutrophils damage capillary wall
Damage to filtration barrier
Proliferation: mesangial expansion, hypercellular
RPG
rapidly crescentic
loop wire
lupus
Fibrinogen
IF
PSG
3 for PSG
type 3 reaction
3 weeks after sore throat
C3 is decreased
lump3 bump3
IF
GP
2 pasture
2 organs involved
type 2 reaction
against 2 x 2 = 4 collagen
linear deposits
IF
Alfort syndrome
4 things
GP + eye + ear
IgA
Henoch-Schloein Purpura
Bergers
Episodic, self resolving hematuria
Pauci immune
ANCA
P-anca
Strauss
Granulomas + eosinophilia
MPA
C-anca
Wegners