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BREAST PATHOLOGY (Benign Tumors (Galactorrhea (Causes (Estrogen excess…

- - - - Unilateral
        
        Finger like projection with a fibrovascular core
        
        Epithelial layer + Myoepithelial layer
        
        Ddx with papillary carcinoma
  - - - Estrogen excess
        
        Cimetidine, Finasteride, Spironolactone, Ketoconazole, Anti-Psychotics, Anabolic Steroids
        
        Klinefelter, Cirrhosis
- - - - Acini and stroma, calcifications
        
        Increased cancer risk
  - - - Cyclic mastalgia
        
        No increased risk of cancer
- - - - Mass, skin dimpling/nipple retraction
      - Stellate infiltration
      - Duct-like structures in desmoplastic stroma
    - - Looks normal: look for dermoplastic stroma, and no second cell type
      - Good prognosis
    - - Cells floating in mucus
      - Good prognosis
      - Elderly women
    - - Plasma cells
      - BRCA-1
- - - - Green nipple discharge
- - - - No mass: presents as micro-calcifications
        
        DDx for calcification
        
        Fat necrosis
        
        Sclerosing adenosis
      - No BM penetration
    - - Necrosis surrounded by calcification in center of the duct