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Cirrhosis Complications (Intro: (Liver functions (Toxin processing: NH3
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Cirrhosis Complications
Intro:
Liver functions
Clotting factors 2, 7, 9, 10
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Toxin processing: NH3
- Hepatic encephalopathy (NH4 in brain)
Pt: Confused, AMS, aterexis (flapping)
Dx: S/s
Tx: Lactulose (1st line)
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bile,
- bilirubin excretion : jaundice
- bile salt excretion : Pruritus
Metabolizes Estrogen
- Appearance symptoms
- Gynecomastia
- Palmar Erythma :hand:
- Spider Angiomata :spider_web:
Portal Vein
- Obstruction causes Portal HTN
- Thrombocytopenia (splenic sequestration)
- Ascites
- Varicies (portal caval shunts)
-
Ascites : Fluid in belly
Is fluid hydrostatically pushed out or osmotically?
- Portal HTN Related
- non portal HTN related
Paracentesis w/
SAAG
-
Hi SAAG ≥1.1
Fluid is mostly water, low albumin
Portal HTN
Cirrhosis
Pt:
- Blulging flanks
- Shifting Dullness
- Fluid Wave :ocean:
Dx:
- Paracentesis: SAAG
- Culture/gram stain/Protein/Cell count
- 1 more item...
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