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Anti-depressant (Causes : (Decrease level Norepinephrine , Serotonin,…

- - - - patients with seasonal affective disorder & major depression
- - - - CITALOPRAM
      - ESCITALOPRAM
      - FLUOXETINE
      - PAROXETINE - Most sedative
      - FLUVAXAMINE
      - SERTRALINE
      - VORTIOXETINE
      - VILAZODONE
      - improved tolerability and side effect profile , safety in overdose, broad spectrum of uses
      - low affinity for histaminergic, alpha1 adrenergic, and muscarinic receptors
      - Withdrawal symptoms can occur if an SSRI is abruptly discontinued (Esp with Paroxetine)
      - takes 4–6 weeks before SSRIs begin to reduce symptoms
    - - Mental confusion , Hallucination,Twitching, Hyperthermia