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Cell to Cell (archaebacteria, eubacteria, protista, fungi, Plantae,…
Cell to Cell
archaebacteria
eubacteria
protista
fungi
Plantae
Animalia
Virus/symbiotic
Unique Organelles
Glycosome
Desmoglycosomes (muscle)
Lyoglycosomes (free)
Lipid droplets
RER
SER
Lysosomes
Vesicles (paramural bodies plants)
Golgi
Mitochondria
Chloroplast
ECM/Receptors
Nucleus
Transosomes
Vacuoles
Plasmodesmata
Peroxisomes
Cytoskeleton
Plastid (pigments)
Melanosomes
Prokaryotic nutrient storing organelles
Organelle Communication
ER/Mito
upregulated in obesity
drives ROS
Affects insulin sensitivity
inflammasome
JNK stress apoptosis
regulates max mito respiration levels but not basal
regulated in muscle
cardiac
skeletal
Neurons
gangliosidosis
alzheimers
senescence
ER/PM
Calcium uptake
cardiac disease
muscle contraction
immune function
plant stress responses
Lipid synthesis
autophagocytosis
sterol uptake
Mito/Peroxisome
b oxidation fats
PM/vacuole
Lipid droplet/ER
Lipid droplet/vacuole
Lipid droplet/PM
peroxisome/PM
Inputs for Communication
Oxidative stress
Starvation
Inflammation
Chronic
Protein misfolding
Environmental
Ethanol
Types of Communication
Direct Contact
Protein translocation
vesicle based
small molecule signaling
lipid mediated
Diseases
Obesity
Malnourishment