Please enable JavaScript.

Coggle requires JavaScript to display documents.

Meningitis (History (S/S (Bacterial meningitis classic triad (Neck…

- - - - Neck stiffness (nuchal rigidity)
      - Fever
      - Headache
    - - Nausea; Vomiting; Photalgia (photophobia); Sleepiness; Confusion; Irritability; Altered mental status (Delirium or Coma)
- - - - Small; pleomorphic; gram-negative coccobacillus that's frequently found as part of the normal flora in the upper respiratory tract. can spread in airborne droplets or by direct contact with secretions.
    - - S pneumoniae
        
        Gram-positive coccus, spread through nasopharynx and bacteremia, or through direct extension from sinusitis or otitis media
    - - Gram-positive coccus that inhabits the lower GI tract and female genital tract.
    - - N meningitidis
        
        Gram-negative diplococcus that is carried in the nasopharynx. Invades by penetrating the airway epithelial surface.
    - - small gram-positive bacillus; a common food contaminant (raw meat; vegetables; milk; cheese)
    - - Aerobic gram-negative bacilli : Escherichia coli; Klebsiella pneumoniae; Serratia marcescens; P aeruginosa; Salmonella sp
    - - Gram-positive cocci that are part of normal skin flora
- - - - Exanthemas; symptoms of pericarditis, myocarditis or conjunctivitis
    - - Nonblanching petechiae and cutaneous hemorrhages
- - - - Divided into
        
        Acute Bacterial Meningitis
        
        Acute onset of meningeal symptoms and neutrophilic pleocytosis
        
        Chronic Meningitis
        
        CSF pleocytosis that persists for longer than 4weeks
    - - Fungal & Parasitic (eg, cryptococcal meningitis, Histoplasma meningitis, and amebic meningoencephalitis)
- - - - Penicillin MIC<0.06mcg/mL
      - Cefotaxime or ceftriaxone MIC >1.0mcg/mL
    - - Beta-lactamase-negative : Ampicillin or Cefotaxime; Ceftriaxone
      - Beta-lactamase-positive : Cefotaxime or Ceftriaxone; Cefepime; Chloramphenicol
    - - Penicillin
    - - Ampicillin or Penicillin G
    - - Cefotaxime or ceftriaxone
    - - Ceftazidime or cefepime
    - - Vancomycin
  - - - Acyclovir (10mg/kg IV every 8hours)
    - - Ganciclovir 5mg/kg IV every 12hours for 21days, and maintenance dosage of 5mg/kg every 24hours
      - Oral valganciclovir (900mg/day)