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KIDNEY DISEASE (Pre-renal AKI (Hypovolaemia (Post-op nasogastric tube,…
KIDNEY DISEASE
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Tubules
Acute tubular necrosis (due to ischaemia e.g. shock, low BP, renal artery stenosis; or due to nephrotoxins)
Genetic conditions
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Affects PCT
Fanconi's syndrome (inadequate reabsorption of glucose, amino acids, uric acid, phosphate & bicarbonate)
Affects CD
Taking too much of a medication e.g. NSAIDs can cause drug metabolites to build up in the medulla, damaging vasa recta
Glomerulus
Primarily nephrotic syndromes (massive proteinuria, hypoalbuminaemia, oedema, hyperlipidaemia)
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Primarily nephritic syndromes (haematuria, oliguria, hypertension, reduced GFR, mild proteinuria)
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