Tuberous Sclerosis (Symptoms (Seizures, Developmental Delays, Behavioral…
Benign tumors may grow on brain and other vital organs.
Only one of these genes needs to be altered for the disorder to be present.
A mutation on the TSC1 and TSC2 gene.
Through examination and MRI or CT of brain.
Many are not diagnosed until later in life.
Presence of seizure and delayed development.
1 to 2 million individuals worldwide
25,000 to 40,000 individuals in the United States
Few inherit the autosomal dominant disorder.
Most cases are new or spontaneous mutations.
70-80% have kidney problems between age 15 - 30.