Please enable JavaScript.

Coggle requires JavaScript to display documents.

HIV (Risk factors for HIV (Needle sticks/IVDA (0.03%, obviously repeat…

- - - - 0.02%
  - - - CXCR4 and CCR5 mutants do not have CD4 drops (immune)
      - slow trending down (3y to get to AIDS)
      - fast trending (1year to get AIDS)
- - - - NNRTI
      - Fusion inhibitors
        
        Protease inhibitor + Ritonavir (low dose)
        
        Entry inhibitors
        
        :pencil2:ritonavir does not increase toxicity
  - - - PrEP (Preexposure prophylaxis)
        
        Tenofovir
        
        Emtricitabine
        
        Pregnancy
        
        "2+1" ideal if known during Pregnancy
        
        If acute presentation, at delivery prevent vertical transmission
        
        AZT
      - Emtricitabine
      - Tenofovir
      - +/- Raltegravir
- - - - :pencil2:HIV Elisa will be negative in the acute setting
      - Dx with PCR to determine the viral load
        
        Tx: 2 + 1 antiretrovirals
        
        :pencil2:Too late to prevent, since inflammatory response mounted. Will have HIV for life
        
        :pencil2:body won't have developed Ab's
  - - - ELISA, HIV ab's then Western Blot
        
        :pencil2:if ELISA is (+) do not tell pt until confirmatory test is (+) also
        
        Other info important to know
        
        CD4 count
        
        Viral load
        
        "where you are going"
        
        2 more items...
        
        Genotype
        
        2 more items...
        
        "Where you are AT"
        
        Takes years to respond
        
        will only get to rise to 300, no matter how compliant
        
        2 more items...
- - - - Nucleus turns DNA into more virus
        
        Packaged virus infects other cell