Please enable JavaScript.

Coggle requires JavaScript to display documents.

PA 6 Neoplasia瘤 (Para-Neoplastic Syndromes (Nerve/Muscle, (Lung ca,…

- - - - 惡性腫瘤或Trousseau綜合徵的徵兆
- - - - similar between the cancer cell and the tissue
      - similarity
    - - no able to see the similarity
      - the tissue is dead and cannot battle
      - no able to see the lymphocyte
      - poor inflammatory reaction
- - - - morphology and architecture
    - - (often classified with CIS(Carcinoma in situ是一組異常細胞,可能會成為癌症)
- - - - UV
        
        BCC
        
        SCC
        
        MM
      - Ionizing(photons光子and particles微粒)
        
        Hematopoetic造血 and Thyroid (90%/15yrs)
        
        Solid tumors either less susceptible受影響 or require a longer latency period延遲時間更長 than LEUK/LYMPH
  - - - • HPV-->SCC (squamous cell carcinoma)
      - • EBV-->Burkitt Lymphoma
      - • HBV-->Hepatocellular Carcinoma(Hepatoma肝癌)
      - • HTLV1-->T-Cell Malignancies
      - • KSHV-->Kaposi Sarcoma
    - - Helicobacter pylori (H. pylori) 幽門桿菌
        
        100% of gastric lymphomas胃淋巴瘤
        
        gastric carcinoma 胃癌
  - - - Complets
        
        initiator and promoter
        
        Incomplete
        
        only initiator
      - Indirect
        
        need to be metabolized to produce effect
        
        Link to individual polimorfisms in enzymes – different susceptibility鏈接到酶中的個體多態性 - 差異易感性
        
        Direct
      - Ex: carbon tetrachloride 四氯化碳
- - - - • adenocarcinoma: gland forming tumor
      - • squamous cell carcinoma鱗狀細胞癌: squamous differentiation
      - • undifferentiated carcinoma: no differentiation
    - - • fibrosarcoma: fibrous tumor
      - • osteosarcoma: bone tumor
      - • liposarcoma脂肪肉瘤: adipous tumor
      - • chrondrosarcoma: cartilaginous tumor
  - - - Basement membrane
      - Capsule
    - - – Unequivocal sign明確徵兆 of malignancy
      - – Lymphatic
      - – Hematogenous 血源性
      - – Seeding of body cavities體腔播種
- - - - fibroma: fibrous tumor
      - osteoma: bone forming tumor
      - chondroma軟骨瘤 : cartilage tumor
    - - • adenoma: tumor forming glands
      - • papilloma: tumor with finger like projections
      - • papillary cystadenoma乳頭狀囊腺瘤: papillalry and cystic tumor forming glands
      - • polyp: a tumor that projects above a mucosal surface
- - - - tonofibrils
      - desmosomes