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Pertussis (General Characteristics (aka "Whooping cough",…
Pertussis
General Characteristics
aka "Whooping cough"
Bordetella pertussis
gram negative
rod
aerobic
human specific
Transmission
respiratory
family transmission
most infectious first two weeks
attach to respiratory epithelial cells
tracheal cytotoxin
incubation 7-10 days
Symptoms
Paroxysmal Stage
low fever
bursts of coughs
high pitched whooping
vomit
normal between whooping bursts
Convalescent Stage
cough subsides
Catarrhal Stage
sneezing
low fever
mild cough
rhinorrhea
Complications
All
pneumonia 23%
convulsions 1.1%
apnea 61%
death 1%
encephalitis 0.3%
Adults & Teens
weight loss 33%
loss of bladder control 28%
passing out 6%
rib fractures 4%
Treatment
vaccine
DTaP (pediatric)
Tdap (adults)
support
hygiene