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HYPERSENSITIVITY (TYPE I (allergy/ immediate) (Immune reactant : IgE,…
HYPERSENSITIVITY
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TYPE II 
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IgG or IgM will bind to cellular antigen, leading to complement activation and cell lysis. IgG also can mediate ADCC with cytotoxic T cell, natural killer cells, macrophages and neutrophils.
Red blood cell destruction after transfusion with mismatched blood type during hemolytic disease of the newborn.
TYPE III
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antigen-antibody complexes are deposited in tissues. Complement activation provides inflammatory mediators and recruits neutrophils. Enzymes released from neutrophils damage tissue.
Post-streptoccocal glomerulonephritis, rheumatoid arthritis, and systemic lupus erythematosus
TYPE IV
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TH 1 cells secrete cytokines, which activates macrophages and cytotoxic T cell
contact dermatitis, type I diabetes melitus, and multiple sclerosis