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ANTI-PARKINSON DRUGS (MOTILIUM (INDICATIONS (organic, infectious, Nausea…
ANTI-PARKINSON DRUGS
MOTILIUM
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MECHANISM OF ACTION
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In domperidone users, especially in adults, extrapyramidal side effects are very rare, but domperidone promotes the release of prolactin from the pituitary
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Its anti-emetic effect may be due to a combination of peripheral (gastrokinetic) effects and antagonism of dopamine receptors in the chemoreceptor trigger zone, which lies outside the blood-brain barrier in the area postrema
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