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DEGENARATIVE DISORDERS (Parkinson disease (management (management of…
DEGENARATIVE DISORDERS
Parkinson disease
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pathophysiology
The essential defect is a depletion of dopamine due to loss in the substantlia nigra , locus ceruleus and other pigmented areas of the brainstem and basal ganglia .
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Assessment
hypokinesia , bradykinesia,tremors,ataxia ,poor postural control
management
management of parkison disease is the directed at controling motor symptoms to enable the patient to remain mobile and independent.
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multiple sclerosis
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clinical manifestation
fatigue,weakness,difficulty with coordination ,loss of balance
pathophysiology
Multiple sclerosis is a progressive disorders of the central nervous system,characterised by demyelination and plaque formation in the brain and spinal chord
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huntington chorea
definition
is a genetic autosomal dominant condition characterised by choreiform movement, akinesia and marked mental deterioration
pathophysiology
is a genetic autosomal dominant condition characterised by choreiform movement ,akinesia and marked mental deterioration ,and ending in total disability
management
Antispasmotic agents may be given to reduce the toxicity of muscles and reduce spasticity in the early stages of the disease
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