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ANTIMYASTHENIC DRUGS (ARICEPT (Nursing considerations (Side effects…
ANTIMYASTHENIC DRUGS
ARICEPT
Mechanism of action
Reversible specific cholinesterase inhibitor.
Active metabolites.
Very long half-life.
Indications
Mild to severe AD.
Nursing considerations
Side effects
Headache.
Fatigue.
Syncope.
Insomnia.
Vomiting.
Bradycardia.
Contraindications
Hypersensitivity.
Sick sinus syndrome.
Gastric ulcers.
Obstructive lung disease.
Route of administration
Orally.
Storage condition
Cool dry place.
Away from sunlight.
Room temperature.
EXELON
Mechanism of action
Selective cholinesterase inhibitor.
Indication
Mild to moderately severe AD
Nursing considerations
Side effects
Nausea.
Tremor.
Agitation.
Anxiety.
Increased sweating.
Weight loss.
Contraindications
Severe liver disease.
Obstructive lung disease.
Asthma.
Gastric ulcers.
Route of administration
Orally.
Transdermal.
Storage condition
Away from sunlight.
Away from children.
Room temperature.
MESTINON
Mechanism of action
Inhibit cholinesterase.
Increase amount of acetylcholine.
Has direct cholinomimetic effect on skeletal muscle.
Indications
Myasthenia gravis.
Nursing considerations
Side effects
Increased salivation.
Abdominal cramps.
Increase bronchial secretions.
Bradycardia.
Sweating.
Contraindications.
Urinary tract obstruction.
Decreased GI motility.
Hyperthyroidism.
Epileptic.
Route of administration
Orally.
Storage condition
Away from sunlight.
Room temperature.
Away from children.
Cool dry place.