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female hormonal drugs (estrogen receptor modulators (side effect (nausea…
female hormonal drugs
estrogen receptor modulators
name
raloxifen
mechanism of action
produce some of the positive effects of estrogen replacement while limiting the adverse effects
increase bone mineral density without stimulating endometrium
indications
prevent oesteoroporosis
treat oesteoporosis in postmenopausal women
contraindications
allergy
pregnancy
lactation
hisory of venous thrombosis
side effect
nausea and vomiting
headache
dizziness
visual changes
mental changes
skin rash
vaginal bleeding
nursing consideration
assess the patient for contraindications
perform physical assessment
assist with pelvic and breast examination
monitor laboratory
route
oral
storage conditions
away from sunlight
away from children
store in a cool dry place
Estrogens
name
estradiol
mechanism of action
affect the release of follicle stimulating hormone and luteinizing hormone
responsible for the proliferation of the endometrial lining
they compete with androgens for receptor sites
loss of oestrogen is responsible for signs and symptoms of menopause in the uterus
indications
used for hormone replacement therapy
used as palliation for discomforts of menopause
treat female hypogonadism and ovarian failure
prevent postpartum breast engorgement
slow bone loss in oesteoporosis
palliation of cancers and that have known receptor sensativity
contraindications
allergy
vaginal bleeding
breast cancer
history of thromboembolic disorders
heavy smoker
hepatic dysfunction
pregnancy
lactating women
renal insufficiency
side effect
nausea and vomiting
abdominal cramps
bloating
acute pancreatitis
dysmenorrhea
headache
edema
route of administration
oral
storage conditions
cool dry place
away from children
away from sunlight
progestins
name
levonorgestrel
mechanism of action
inhibit secretion of FSH and LH
Transform the proliferative endometrium into secretory endometrium
prevent follicle maturation and ovulation and uterine contraction
prevent release of Gonadotropin releasing hormone
circulate progestins and estrogens
indications
inhibit secretion of fsh and lh
circulate progestins and oestrogens
prevent release of Gonadotropin-release hormone
Transform the proliferative endometrium into secretory endometrium
contraindications
pelvic inflammation
sexually transmitted diseases
endometriosis
pelvic surgery
drosperinone
epilepsy
migraine headache
side efffect
headache
nervousness
constipation
breast enlargement
perineal pain
abortion PID
Expulsion of the intrauterine device
storage conditions
cool dry place
away from sunlight
away from children
route of administration
oral
fertility drug
name
cetrorelix
mechanism of action
stimulate follicles
stimulate ovulation and hypothalumus
leads to ovarian follicular development
contraindications
allergy to fertility drugs
primary ovarian failure
ovarian cysts
lactation
pregnancy
uterine bleeding
side effects
risk of multiple births
birth defect
abdominal pain
pleural effusion
headache
uterine bleeding
bloating
indications
treat infertility in women
stimulate multiple follicle development
inhibit premature LH in women
used for vitro fertilisation
route
oral
storage conditions
cool dry place away from sunlight and out of reach of children
uterine motility drugs
name
oxytocin
mechanism of action
stimulate uterine contractions
stimulate the lacteal glands in the breast to contract
promote milk ejection
stimulate uterine contractions
indications
prevent postpartum heamorrhage
treat uterine atony after delivery
contraindications
allergy
cephalopelvic disproportion
early pregnancy
coronary diseases
hypertension
unfavourable fetal position
side effect
nausea
blood pressure changes
weak pulse
coldness in the extremities
chest pain
delirium
route
intramuscular or intraveneous