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SKELETAL MUSCLE RELAXANTS (BACLOFEN (Indications (Muscle spasticity.,…
SKELETAL MUSCLE RELAXANTS
BACLOFEN
Mechanism of action
Inhibit monosynaptic reflexes.
Inhibit polysynaptic reflexes.
Hyperpolarization of afferent terminals.
Indications
Muscle spasticity.
Spinal cord injury.
Multiple sclerosis.
Hiccups.
Muscle spasm.
Nursing considerations
Side effects
Headache.
Transient drowsiness.
Weakness.
Fatigue.
Confusion.
Insomnia.
Depression.
Contraindications
Abrupt discontinuation.
Cerebral palsy.
Head trauma.
Diabetes mellitus.
Seizure disorder.
Stroke.
Intracranial bleeding.
Route of administration
Orally.
Storage condition
Stored in a container.
Kept at room temperature.
Kept out of reach of children
METHOCARBAMOL
Indications
Skeletal muscle conditions.
To treat muscle pain.
To treat muscle injury.
Mechanism of action
It has no direct action.
It has mechanism of striated muscle.
It has a mechanism of motor end plate.
It has a mechanism of nerve fibre.
Nursing considerations
Side effects
Upset stomach.
Sleep problems.
Blurred vision.
Memory problems.
Loss of balance.
Vomiting.
Contraindications
History of angioedema.
Renal failure.
Pregnancy.
Breast feeding.
Hepatic disease.
Seizure disorder.
Hypotension.
Route of administration
Orally
Storage condition
Room temperature
Away from heat.
Stored in a container.
TIZANIDINE
Mechanism of action.
Central 2 adrenergic receptor agonis
Reduce spasticity
Increase presynaptic inhibition of motor neurons
Reduce facilitation of spinal motor neurons
Relax muscle tone
Indications
Spasticity
Blocks nerve impulse.
Nursing considerations.
Side effects.
Weak/shallow breathing.
Confusion
Hallucination
Vomiting
Constipation
Pain when urinating.
Contraindications.
Heart failure.
Hypertension.
Liver injury
Psychotic symptoms.
Sedation
Withdrawal adverse reactions.
Route of administration.
Orally.
Storage condition
Cool, dry place.
Away from heat.
Kept out of reach of children.
DANTROLENE
Mechanism of action
Depresses excitation contraction coupling.
Decrease free intracellular calcium concentration.
Indications
Prevent muscle stiffness.
Prevent muscle spasm.
Treat stroke.
Treat cerebral palsy.
Treat spinal cord injury.
Nursing considerations
Contraindications
Cirrhosis.
Hepatitis.
Breathing disorder.
Liver disease.
Heart disease.
Side effects
Muscle weakness.
Severe diarrhoea.
Severe drowsiness.
Vomiting.
Tired feeling.
Route of administration
Orally.
Storage condition
Store in a container.
Room temperature.
Kept out of reach of children.