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nitrate drugs isosorbide mononitrate (*side effects ((nausea,, vomiting,,…
nitrate drugs isosorbide mononitrate
*side effects
skin warmth or redness,
tingling under your skin,
headache
nausea,
vomiting,
constipation,
mechanism of action
The net effect of isosorbide mononitrate is a reduced load on the heart and better oxygen supply to the myocardium. Isosorbide mononitrate is intended for use in the prophylactic treatment of angina pectoris. Mechanism of action: Like all organic nitrates, isosorbide mononitrate acts as a donor of nitric oxide
contraindications
Hypersensitivity to organic nitrates.
PDE-5 inhibitors concomitant use can cause severe hypotension, syncope, or myocardial ischemia.
Concomitant administration with guanylate stimulator riociguat (may cause hypotension)
route of administration
Tablets once daily
storage
at room temperature away from light and moisture. Do not store in the bathroom.
indications
Isosorbide mononitrate is a prescription drug indicated for the prevention of angina pectoris due to coronary artery disease
The onset of action of oral isosorbide mononitrate is not sufficiently rapid for this product to be useful in aborting an acute anginal episode.