Please enable JavaScript.

Coggle requires JavaScript to display documents.

Male Hormonal drugs (Androgens (Indications (used for treatment of…

- - - - Growth and development of male sex organs and the maintenance of secondary male sex characteristics.
      - Increase the retention of nitrogen, sodium, potassium, and phosphorus and decrease the urinary excretion of calcium.
      - Increase protein anabolism and decrease protein catabolism.
      - Increase the production of red blood cells.
  - - - Allergy to androgens or other ingredients in the drug. Prevent hypersensitivity reactions.
      - Pregnancy, lactation. Potential adverse effects on the neonate. It is not clear whether androgens enter breast milk.
      - Presence of prostate or breast cancer in men. Aggravated by the testosterone effects of the drug.
      - Liver dysfunction, CV disease. Can be exacerbated by the effects of the hormones.
      - Topical forms of testosterone have a Black Box Warning alerting user to the risk of virilization in children who come in contact with the drug from touching the clothes and skin of the man using the drug.
      - Danazol has Black Box warning regarding the risk of thromboembolic events, fetal abnormalities, hepatitis, and intracranial hypertension.
    - - Intracranial hypertension
      - Increased blood pressure
      - Thromboembolism
      - Anxiety
      - Depression
      - Dizziness
      - Urticaria
    - - Intramuscular
      - Buccal
      - Dermal
    - - Store away from the light
      - Avoid moist
      - Store at room temperature between 15 to 30 degrees
- - - - Allergy to androgens or other ingredients in the drug. Prevent hypersensitivity reactions.
      - Pregnancy, lactation. Potential masculinization in neonates.
      - Liver dysfunction. Drug is metabolized in the liver and are known to cause hepatic toxicity.
      - Coronary disease. Potentional increase in cholesterol level through the effect of the drug on the liver.
      - Prostate/breast cancer in males. Exacerbated by the effects of these drugs.
    - - Nausea
      - vomiting
      - skin color changes,
      - skin color changes,
      - Hair loss
    - - Store in room air temperature between 15 to 30
      - Avoid moisture
      - Store away from heat
    - - Orally
- - - - The desired and beneficial actions of drugs for treatment of penile erectile dysfunction are as follows:
      - Alprostadil acts locally to relax the vascular smooth muscle and allow filling of the corpus cavernosum, causing penile erection
      - act to increase nitrous oxide levels in the corpus cavernosum. Nitrous oxide activates the enzyme cyclic guanosine monophosphate (cGMP) to cause smooth muscle relaxation and increased flow of blood.
    - - Treatment of penile erectile dysfunction.
      - including for men with diabetes mellitus.
    - - flushing (warmth, redness, or tingly feeling)
      - headache, dizziness
      - abnormal vision (blurred vision, changes in color vision)
      - runny or stuffy nose, nosebleeds
      - sleep problems (insomnia)
      - muscle pain, back pain
      - upset stomach.
    - - Recommended Storage: Store at 25°C
      - Avoid heat and light
    - - Orally