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Skeletal muscle relaxant (Baclofen (contraindications (Intrathecal…
Skeletal muscle relaxant
Baclofen
Mechanism of action
Baclofen attaches to the GABA B receptors in the brain and spinal cord, causing the release of GABA, the CNS’s major inhibitory neurotransmitter. The mechanism of the effects on alcohol craving and anxiety are poorly understood.
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storage conditions
Storage temperature should not exceed 25 ° C. If the storage conditions of Baclofen are not observed, the drug loses its
Dantrolen
Mechanism of action
It is a phenytoin analogue àbut its site for antispastic action lies ouside the CNS; It acts directly at the contractile mechanisms of voluntary muscle by reducing depolarization induced Ca+2 release from the sarcoplasmic reticulum
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storage conditions
keep this medication in the container it came in, tightly closed and out of the reach of children. Store it at room temperature.
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Carisopradol
Mechanism of action
This drug works in the kidneys by inhibiting an enzyme called carbonic anhydrase. Carbonic anhydrase is the enzyme responsible for moving bicarbonate (sodium bicarbonate) (a base) from the kidney back into the blood stream.
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storage conditions
. Carisoprodol should only be used for short periods (up to two or three weeks) because there is no evidence of its effectiveness in long term use and most skeletal muscle injuries ..
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