Skeletal muscle relaxant
Baclofen
Dantrolen
Mechanism of action
Baclofen attaches to the GABA B receptors in the brain and spinal cord, causing the release of GABA, the CNS’s major inhibitory neurotransmitter. The mechanism of the effects on alcohol craving and anxiety are poorly understood.
Indications
Muscle spasm
Relief of spasticity of voluntary muscle
myoclonus
Multiple sclerosis
Side effects
Headache
Constipation
nausea
sleep problems
contraindications
Intrathecal admnistration
Abrupt discontinuation
Geriatric
Diabetes mellitus
Seizure disorders
route of adminstration
Oral administration
storage conditions
Storage temperature should not exceed 25 ° C. If the storage conditions of Baclofen are not observed, the drug loses its
Mechanism of action
It is a phenytoin analogue àbut its site for antispastic action lies ouside the CNS; It acts directly at the contractile mechanisms of voluntary muscle by reducing depolarization induced Ca+2 release from the sarcoplasmic reticulum
Contraindications
Lung disease
Hepatitis
Liver problems
Chronic obstructive lung disease
Side effects
Dizziness
drowsiness
Tired feeling
storage conditions
keep this medication in the container it came in, tightly closed and out of the reach of children. Store it at room temperature.
Route adminstration
Orally
Indications
Motor neuron disorders
cerebral palsy
Chronic spasticity
Carisopradol
Mechanism of action
This drug works in the kidneys by inhibiting an enzyme called carbonic anhydrase. Carbonic anhydrase is the enzyme responsible for moving bicarbonate (sodium bicarbonate) (a base) from the kidney back into the blood stream.
indications
If you have ever had porphyria.
If you are taking meprobamate
It is used to calm muscles.
Side effects
Dizziness.
Feeling sleepy.
Feeling very tired or weak.
Seizures
contraindicatons
Breatfeeding
pregnancy women
storage conditions
. Carisoprodol should only be used for short periods (up to two or three weeks) because there is no evidence of its effectiveness in long term use and most skeletal muscle injuries ..
route of admnistration
Orally
Acute intermittent
Carbamate hypersensitivity