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MALE AND FEMALE HORMONAL DRUGS (STORAGE (Store at room temperature…
MALE AND FEMALE HORMONAL DRUGS
ESTRADIOL
ROUTE OF ADMINISTRATION
Administered orally
MECHANISM OF ACTION
is a nuclear hormone, meaning it acts on receptors present inside the cell,
that can activate or deactivate transcription in the nucleus.
Estradiol interacts with a target cell receptor (Erα or Erβ) within the cytoplasm of the cell.
Once estradiol is bound to its receptor ligand,
the receptor can enter the nucleus of the target cell and induce the formation of messenger RNA.
This mRNA then interacts with ribosomes to produce specific proteins that exert the effects of estradiol on the cell.
INDICATIONS
For treatment of moderate to severe vasomotor symptoms (hot flashes) of menopause and/or related genitourinary symptoms
including atrophic vaginitis, vulvar atrophy, whether menopause is natural or surgical
SIDE EFFECTS
Stomach upset,
nausea/vomiting,
bloating, breast tenderness,
headache, or weight changes may occur.
CINTRAINDICATIONS
Undiagnosed abnormal genital bleeding.
Known, suspected or history of cancer of the breast
Known or suspected estrogen-dependent neoplasia.
Active deep vein thrombosis, pulmonary embolism or history of these conditions.
STORAGE
low temperature
away from light and moisture
keep away from children
DANAZOL
ROUTE
Oally
MECHANISM OF ACTION
reduces estrogen production and levels, it has functional antiestrogenic properties.
The combination of its antiestrogenic, androgenic, and progestogenic or antiprogestogenic actions
cause atrophy of the endometrium, which alleviates the symptoms of endometriosis
INDICATIONS
is used primarily in the treatment of endometriosis.
namely in the management of menorrhagia, fibrocystic breast disease,
immune thrombocytopenic purpura, premenstrual syndrome,
breast pain, and hereditary angioedema.
CONTRAINDICATIONS
Markedly impaired hepatic, renal, or cardiac function.
Pregnancy ,Breast feeding.
Androgen-dependent tumor.
SIDE EFFECTS
weight gain,
acne,
oily skin or hair,
sweating,hair loss,
Voice changes,sore throat,
STORAGE
Store at room temperature between(15-30 degrees C) away from light and moisture
Do not store in the bathroom
Keep all medications away from children and pets
Do not flush medications down the toilet or pour them into a drain unless instructed to do so.
Properly discard this product when it is expired or no longer needed