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Pathway flux Cofactors/inhibitors (SAM limitation (MetK (Yes, No), SAM…
Pathway flux
Cofactors/inhibitors
SAM limitation
MetK
Yes
No
SAM transporter
Yes
No
[Fe-S] limitation
Fe & Cys
Yes
No
SUF
Yes
No
Pellet colour?
SAM byproducts inhibition
MtnN
Yes
No
AchY
Yes
No
PLP limitation
Yes
No
NADPH limitation
NADPH transfer
FldA-FPR
No
Yes
NADPH pools
Yes
No
BioB inhibition by DTB and/or 9M-DTB
Yes
No
CoA/ACP limitation
Yes
No
Drop in BTN
Fed vs. De Novo DTB
Protein resources
and/or complexes
BioFKD
BioD
BioFAD