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Oncology (Cytotoxic drugs (S/E of traditional cytotoxics (Myelosuppression…

- - - - Dose-related, non-reversible, lifetime dose
- - - - age
      - chemotherapy agent
      - total dose adminstered
- - - - VEGF
        
        Hand and foot toxicities, LV dysfunction, HTN
      - EGFR
        
        Cutaneous A/E = pain + pruritis
      - HER2 (e.g. trastuzumab)
        
        Cardiotoxicity (monitor LVEF)
      - JAK
        
        Haematological
      - ALK
        
        Pneumonitis