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ANTIFUNGAL DRUGS (Bifonazole cream 1% (side effects (burning, pruritis,…
ANTIFUNGAL DRUGS
Bifonazole cream 1%
mechanism of action
fungastatic against yeast
fungicidal against dermatophytes
indications
mycoses of skin caused by dermatophytes and yeast
contraindications
hypersesitivity to benzyl alcohol
polysorbate
side effects
burning
pruritis
erythema
storage
store below 25 degrees celcius
keep reach out of children
route of administration
applied thinly to affected area
rubbed into skin once daily before sleeping
Clotrimazole cream
mechanism of action
an imidazole
inhibits lipid synthesis in fungal cell membranes
indications
vaginal candidiasis
cutaneous candidiasis
dermatomycoses
contraindications
during pregnancy
during breastfeeding
abdominal pain
side effects
oedema
burning
irritation of skin
abdominal pain
storage
store at room temperature away from excess heat and moisture
reach out of children
route of administration
gently massage cream into affected skin areas 2-3 times daily
Econazole cream
mechanism of action
inhibits RNA synthesis
indications
vulvovaginal candidiasis tinea pedis
contraindications
tobacco smoking
during pregnancy
during breastfeeding
side effects
burning
irritation of the skin
pruritis
storage
avoid exposure to heat
do not freeze
do not refrigerate
route of administration
cream rubbed into affected and surrounding area 2-3 times daily
Amorolfine
mechanism of action
broad spectrum
topical antimycotic
indications
onychomycoses caused by yeast and moulds
contraindications
during pregnancy
breastfeeding
side effects
itching
pruritis
nail discolouration
route of administration
apply nail lacquer to affected finger / toe 1-2 times weekly