Antifungal drugs.
Fluconazole.
Mechanism of action.
Amphotericin B
Mechanism of action.
Clotrimazole.
Mechanism of action.
Nystatin.
Mechanism of action.
Indications.
Nursing considerations.
Contraindications.
Side effects.
Upset stomach.
Heartburn.
Loss of appetite.
Headache.
Diarrhea.
Abdominal pains.
Dizziness.
Liver problems.
Vaginal candidiasis.
Oropharyngeal candidiasis.
Cryptococcal meningitis
Esophageal candidiasis.
Storage.
Route of administration.
Pregnancy
Chronic kidney disease
Hypersensitivivty.
Store at 30 degrees Celsius.
Orally.
Protect it from freezing.
Discard it after 2 weeks if unused.
Inhibits the fungal cytochrome enzyme demethylase.
The inhibition prevents the conversion of lanosterol to ergosterol,
Increases permeability of the membranes of schistosome cells towards calcium ions.
Indications.
Cryptococcosis.
Systemic candidiasis.
Aspergillosis.
Contraindications.
Systemic mastocytosis.
Low amount of magnesium in the blood.
Kidney disease with reduction in kidney function.
Allergies to rotavirus vaccine.
Side effects.
Vomiting.
Anorexia.
Tachypnea.
Fever.
Hypotension.
Headache.
Storage
Stored in the refrigerator.
Protect against exposure to light.
Route of administration.
Slow intravenous infusion.
Indications.
Nursing considerations.
Vaginal infection
Esophageal candida infections.
Mucosal infections.
It binds to ergosterol, a major component of fungal cell membrane.
Once present in sufficient concentration, it forms pores in the membrane that lead to potassium leakage, acidification and death of the fungus.
Side effects.
Diarrhea.
Abdominal pains.
Rash.
Itching.
Contraindications.
Hypersensitivity.
Storage.
Stored at 15-30 degrees celsius.
Protected from light.
Keep out of reach of children.
Route of administration.
Orally.
Tachycardia.
Vomiting.
It works to kill the individual candida or fungal cells by altering the permeability of the fungal cell wall.
It binds to phospholipid in the cell membrane and inhibit the biosynthesis of ergosterol and other sterols required for the cell membrane production.
This leads to the cells death via loss of intracellular membranes.
Indications.
Skin infections.
Ringworms
Athlete's foot.
Jock itch.
Nursing considerations.
Contraindications.
Pregnancy.
Contraceptive devices.
Fever.
Hypersensitivity.
Children.
Vaginal discharge.
Side effects.
Elevated enzymes.
Vaginal pains.
Skin irritation.
Vaginal irritation.
Storage.
Stored at 15-30 degrees Celsius.
Stored at a dry place.
Protect it from light.
Must not be stored at hot or moist place.
Route of administration.
Orally.
Topically.
Intravaginally.
Induces contraction of the parasites, resulting in paralysis in the contracted state.