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Antifungal drugs. (Amphotericin B (Side effects. (Vomiting., Anorexia.,…
Antifungal drugs.
Amphotericin B
Mechanism of action.
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Induces contraction of the parasites, resulting in paralysis in the contracted state.
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Fluconazole.
Mechanism of action.
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The inhibition prevents the conversion of lanosterol to ergosterol,
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Clotrimazole.
Mechanism of action.
It works to kill the individual candida or fungal cells by altering the permeability of the fungal cell wall.
It binds to phospholipid in the cell membrane and inhibit the biosynthesis of ergosterol and other sterols required for the cell membrane production.
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Nystatin.
Mechanism of action.
It binds to ergosterol, a major component of fungal cell membrane.
Once present in sufficient concentration, it forms pores in the membrane that lead to potassium leakage, acidification and death of the fungus.
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