Please enable JavaScript.
Coggle requires JavaScript to display documents.
antiarthritic drug (naproxen sodium (aleve) (side effects (frequent…
antiarthritic drug
naproxen sodium (aleve)
mechanism of action
an NSAID that produces analgesic and anti-inflammatory effect by inhibiting prostaglandins synthesis.
-
indication
osteoarthritis, acute gouty arthritis, dysmenorrhea
-
side effects
frequent
nausea, constipation, abdominal cramps or pain, heart burn, somnolence
occasional
stomatitis, diarrhea, fluid retention
-
storage condition
cool dry place, away from direct sunlight.
route of administration
oral, swallow enteric-coated tablet whole; scored tablets may be broken or crushed.
-
etanercept (enbrel)
mechanism of action
a protein that binds to tumour necrosis factor (TNF), blocking its interaction with cell surface receptor
elevated levels of TNF, which is involveds in inflamatory and immune responces, are found in the synovial fluid of rheumatoid arthritis patient.
indication
rheumatoid arthritis, juvenile rheumatoid arthritis, plaque psoriasis
contraindication
serious active infection or sepsis, hypersensitivity to etanercept, significant hematologic abnormalities
latex hypersensitivity(auto-injection), benzyl alcohol hypersensitivity (diluent for powder for injection)
side effect
frequent
injection site erythema, pruritus pain and swelling
occasional
headache, asthenia, abdominal pain, rash, rhinitis
rare
sinusitis, allergic reaction, lupus-like symptoms
storage condition
-
once reconstituted, the drug may be stored for 14 days in the refrigerator
route of administration
subcutaneously inject into the abdomen, thigh, or upper arm
-
prednisone
mechanism of action
an adrenocortical steriod that inhibit accumulation of inflammatory cells at inflammation site, lysosomal enzyme release and synthesis.
indication
nonendocrine disorder: arthritis, rheumatic carditis; skin disease,allergic, collagen
contraindication
acute superficial herpes simplex keratitis, systemic fungal infection
side effect
frequent
insomia, heart burn, abdominal distention, increased sweating, increase appetite, facial flushing, delayed wound healing
occasional
edema, change of skin color, frequent urination
rare
tachycardia, rash, hallucination, depression
-
-