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Resp Drugs (Brit Thoracic Guidelines for asthma (Step 2: + Beclomethasone,…
Resp Drugs
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Steroids
Inhibits mast cells, histamine, cytokines
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Beclomethasone
Inhibits cytokines, Phospholipase inhibition.
β2 adrenergic agonists
Long acting (LABA): Salmeterol, formoterol (Preventer, not reliever)
adenylyl cyclase -> 2nd messenger cAMP -> MLCK inhibited. Lower Ca2+ causes relaxation and bronchodilation
Short acting SABA): Salbutamol,
Theophylline
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Phosphodiesterase inhibitor, adenosine blocker.
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