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Marijuana's effects (long term effects (research (Ex: Rats (+THC) =>…

- - - - ~4,000 young adults, > 25-year period until mid-adulthood
      - cumulative lifetime exposure to marijuana => lower scores
      - not affect other cognitive abilities
    - - marijuana use disorder => loss 6 or up to 8 IQ points
      - not recover the lost IQ points.
    - - ages 9 to 12, before use & ages 17 to 20
      - no predictable difference was found between twins
      - => IQ declines caused by shared familial factors
- - - - precede use of other licit
      - development of addiction to other substances
      - Study: adults: marijuana use- more likely- develop an alcohol use disorder-3 years
      - link to nicotine addiction.
    - - Early exposure - adolescent rodents - decrease reactivity of brain dopamine reward centers
      - => explain the increased vulnerability for addiction to other substances of human
      - show THC’s ability to "prime" the brain => enhance responses to other drugs
      - Ex: rats (+THC) => heightened behavioral response: further exposed to THC + other drugs (morphine)—a phenomenon called cross-sensitization.
    - - pp use => do not use other "harder" substances.
      - cross-sensitization is not unique to marijuana
        (Alcohol and nicotine)
- - - - relaxation & euphoria,
      - some: anxiety, fear, distrust, or
        panic
      - reasons: takes too much, unexpectedly high potency, or inexperienced.
      - large doses => acute psychosis (hallucinations, delusions & a loss of the sense of personal identity)
    - - THC + other chemicals pass from the
        lungs into the blood stream
      - rapidly carry to the brain.
      - smoking/ eating
        
        in foods or beverages, effects after 30 mins - 1 hour, last many hours.
        
        smoking: immediately experience a pleasant euphoria & sense of relaxation, last for 1-3 hours
    - - direct relationship: blood THC concentration
        & impaired driving ability.
      - European studies - drivers (+THC) blood-twice culpable for a fatal crash
      - impairs judgment, motor coordination, and reaction time,
      - most frequently- blood of drivers-in vehicle crashes (+fatal ones)
      - risk= marijuana+alcohol=> greater
      - 3-7 times more-responsible- incident