Types of Hormonal and Metabolic Dysfunction
SIADH
Diagnostic Criteria
Treatment
Clinical Manifestations
Anorexia, nausea, vomiting, headache, irritability, disorientation, muscle cramps, weakness.
Decreased, concentrated urine output
Hypotonicity
Decreased urine volume
Hyponatremia
Highly concentrated urine with high sodium content
Absence of renal, adrenal, or thyroid abnormalities
Removal of DIADH
Water restriction
Hypertonic intravenous (IV) solutions
Diabetes Insipidus (DI)
Clinical Manifestations
Diagnostic Criteria
Treatment
Polyuria
Excessive thirst
Hypersomality, severe dehydration
(Physical exam) dehydration, enlargement of bladder
(Laboratory measures) Serum solute concentration, ADH levels, urine-specific gravity
Urine specific gravity of 1.005 of less, urine osmolality less than 200 mOsm/kg
(Pharmacologic treatment) Desmopressin
Hydration
Hyperthyroidism
Treatment
Diagnostic Criteria
Clinical Manifestations
Exophthalmos
Gorier
Weight loss, agitation, restlessness, sweating, heat intolerance, diarrhea, tachycardia, palpations, tremors, fine hair, oily skin, irregular menstruation
Medications that block thyroid hormone production
Ablation of the thyroid gland
TSH levels
Serum-free thyroxine measurement
(Physical exam) enlarged thyroid gland, protrusion of eyes